Abstract Probabilistic sentential decision diagrams (PSDDs) are a tractable representation of structured probability spaces, which are characterized by complex logical constraints on what constitutes a possible world. We develop general-purpose techniques for probabilistic reasoning and learning with PSDDs, allowing one to compute the probabilities of arbitrary logical formulas and to learn PSDDs from incomplete data. We illustrate the effectiveness of these techniques in the context of learning preference distributions, to which considerable work has been devoted in the past. We show, analytically and empirically, that our proposed framework is general enough to support diverse and complex data and query types. In particular, we show that it can learn maximum-likelihood models from partial rankings, pairwise preferences, and arbitrary preference constraints. Moreover, we show that it can efficiently answer many queries exactly, from expected and most likely rankings, to the probability of pairwise preferences, and diversified recommendations. This case study illustrates the effectiveness and flexibility of the developed PSDD framework as a domain-independent tool for learning and reasoning with structured probability spaces.