Abstract To save the labeling efforts for training a classi- fification model, we can simultaneously adopt Active Learning (AL) to select the most informative samples for human labeling, and Semi-supervised Learning (SSL) to construct effective classififiers using a few labeled samples and a large number of unlabeled samples. Recently, using Transfer Learning (TL) to enhance AL and SSL, i.e., T-SS-AL, has gained considerable attention. However, existing T-SS-AL methods mostly focus on the situation where the source domain and the target domain share the same classes. In this paper, we consider a more practical and challenging setting where the source domain and the target domain have different but related classes. We propose a novel cross-class sample transfer based T-SS-AL method, called CCSS-AL, to exploit the information from the source domain. Our key idea is to select samples from the source domain which are very similar to the target domain classes and assign pseudo labels to them for classififier training. Extensive experiments on three datasets verify the effificacy of the proposed method.