Abstract Pattern-based labeling methods have achieved promising results in alleviating the inevitable labeling noises of distantly supervised neural relation extraction. However, these methods require significant expert labor to write relation-specific patterns, which makes them too sophisticated to generalize quickly. To ease the labor-intensive workload of pattern writing and enable the quick generalization to new relation types, we propose a neural pattern diagnosis framework, DIAG-NRE, that can automatically summarize and refine highquality relational patterns from noise data with human experts in the loop. To demonstrate the effectiveness of DIAG-NRE, we apply it to two real-world datasets and present both significant and interpretable improvements over state-of-the-art methods. Source codes and data can be found at https://github. com/thunlp/DIAG-NRE.