Abstract The well-known problem of knowledge acquisition is one of the biggest issues in Word Sense Disambiguation (WSD), where annotated data are still scarce in English and almost absent in other languages. In this paper we formulate the assumption of One Sense per Wikipedia Category and present OneSeC, a language-independent method for the automatic extraction of hundreds of thousands of sentences in which a target word is tagged with its meaning. Our automaticallygenerated data consistently lead a supervised WSD model to state-of-the-art performance when compared with other automatic and semi-automatic methods. Moreover, our approach outperforms its competitors on multilingual and domain-specific settings, where it beats the existing state of the art on all languages and most domains. All the training data are available for research purposes at http://trainomatic.org/onesec