Abstract
We introduce a new regression framework, Gaussian process regression networks (GPRN), which combines the structural properties of Bayesian neural networks with the nonparametric flexibility of Gaussian processes. GPRN accommodates input (predictor) dependent signal and noise correlations between multiple output (response) variables, input dependent length-scales and amplitudes, and heavy-tailed predictive distributions. We derive both elliptical slice sampling and variational Bayes inference procedures for GPRN. We apply GPRN as a multiple output regression and multivariate volatility model, demonstrating substantially improved performance over eight popular multiple output (multi-task) Gaussian process models and three multivariate volatility models on real datasets, including a 1000 dimensional gene expression dataset.